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  June 29, 2012                  
me+ME:  Qualification on mB12 protocol and M.E. Resources
This is what the title says, and perhaps should have been added to yesterday's bit about my mB12 protocol, but then it was too late in the day when I thought of it to do so yesterday.

So just in case:

                Qualification on mB12 protocol and M.E. Resources

Absolutely nothing I wrote or will write on my site is intended as a medical recommendation: All I do is (1) report my own findings and (2) provide evidence relating to M.E. that usually was written by others.

What you do with the information I provide is your own responsibility.

The reason the information about M.E. on my site is on my site is generally either that it is relevant for my own interests and concerns (being ill with a repeated diagnosis of M.E. or M.E./F.M. since January 1, 1979, and getting no help beyond minimal dole, while receiving much discrimination) or else that I think it may be of interest to others with M.E. or who are interested in M.E.

The reasons the information about the mB12-protocol that I use is on my site are that it is relevant to my own interests and concerns; that it may be helpful to others; and that I would like to see more research into the relation between mB12 and metafolate, especially, and M.E., and other medical conditions, especially such conditions that are like M.E. (F.M., Lyme Disease) or involve people with insufficient energy to function normally.

Anyway... the above is self-evident to me, but I thought I shouid spell it out.

Incidentally, as regards methylfolate, I added an interesting article to M.E. Resources, that you also can find here:

Novel Therapeutics for Depression: L-methylfolate as a Trimonoamine Modulator and Antidepressant-Augmenting Agent

This ends as follows (and is informative about l-methylfolate):


L-methylfolate, also known as MTHF (methyltetrahydrofolate), acts as a trimonoamine modulator to boost the synthesis of the three monoamines: DA, NE, and 5-HT.  This action may provide antidepressant efficacy when L-methylfolate is given as an augmenting agent to depressed patients unresponsive to traditional antidepressants. L-methylfolate may be especially useful in depressed patients who have the genotype coding for an enzyme that causes inefficient synthesis of L-methylfolate, and for those individuals who are folate deficient, including patients whose folate deficiency is secondary to the administration of various anticonvulsant mood stabilizers.

I think the relation to depression is interesting, and apart from that I am interested in knowing more about "patients who have the genotype coding for an enzyme that causes inefficient synthesis of L-methylfolate".

Then again, it should be clear that any relation between what the article is about and M.E./C.F.S. is speculative. And I am listing the article only because I have a repeated medical diagnosis of M.E./F.M. and found empirically that
methylfolate may help me some.

There is more information about M.E. on my site in M.E.-Resources which is these days quite often consulted, and indeed contains a lot of information that may be useful to people with M.E. or their caretakers.

Corrections, if any are necessary, have to be made later.


As to ME/CFS (that I prefer to call ME):

1.  Anthony Komaroff Ten discoveries about the biology of CFS (pdf)
3.  Hillary Johnson The Why
4.  Consensus of M.D.s Canadian Consensus Government Report on ME (pdf)
5.  Eleanor Stein Clinical Guidelines for Psychiatrists (pdf)
6.  William Clifford The Ethics of Belief
7.  Paul Lutus

Is Psychology a Science?

8.  Malcolm Hooper Magical Medicine (pdf)
 Maarten Maartensz
ME in Amsterdam - surviving in Amsterdam with ME (Dutch)
 Maarten Maartensz Myalgic Encephalomyelitis

Short descriptions of the above:                

1. Ten reasons why ME/CFS is a real disease by a professor of medicine of Harvard.
2. Long essay by a professor emeritus of medical chemistry about maltreatment of ME.
3. Explanation of what's happening around ME by an investigative journalist.
4. Report to Canadian Government on ME, by many medical experts.
5. Advice to psychiatrist by a psychiatrist who understa, but nds ME is an organic disease
6. English mathematical genius on one's responsibilities in the matter of one's beliefs:

7. A  space- and computer-scientist takes a look at psychology.
8. Malcolm Hooper puts things together status 2010.
9. I tell my story of surviving (so far) in Amsterdam/ with ME.
10. The directory on my site about ME.

See also: ME -Documentation and ME - Resources
The last has many files, all on my site to keep them accessible.


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